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Pharmaceutical Companies

What are the Top Pharmaceutical Companies in the World?

The Industry has shown strong growth for many years with 2016 being no exception. Worldwide revenue has exceeded 1 Trillion US Dollars and projected to continue to grow strongly fueled by ageing population and a worldwide growth in consumer spending power.

Here is a list of top 15 world’s largest pharmaceutical companies based on 2016 revenue.

Top Pharmaceutical Companies

15. Bristol-Myers Squibb (US) 

Revenue: $19,40 billion
Revenue from Pharmaceutical Drug Sales:$19,40 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $.53 billion
Number of Employees: 25,100
Revenue Per Employee: $777,000

Bristol-Myers Squibb is an American pharmaceutical company that manufactures prescription pharmaceuticals in several therapeutic areas, including cancer, HIV/AIDS, cardiovascular disease, diabetes, hepatitis, rheumatoid arthritis and psychiatric disorders.

Top Pharmaceutical Companies

14. Eli Lilly (US) 

Revenue: $21,22 billion
Revenue from Pharmaceutical Drug Sales: $18,060 billion
Percent of Revenue From Pharmaceutical Drug Sales: 85%
Estimated R&D Spend: $5.24 billion
Number of Employees: 41,975
Revenue Per Employee: $505,000

Eli Lilly is an American global pharmaceutical company. It was founded by Eli Lilly in 1876 and has its headquarters in Indianapolis, Indiana in the United States. The world owes Lilly for the first mass-production of Penicillin, Salk Polio vaccine and insulin and is the largest producer and distributor of psychiatric medications in the world. Other drugs produced by Lilly are namely Arzoxifine, Efient, Olanzapine, etc.

Top Pharmaceutical Companies

13. Teva Pharmaceutical Industries Ltd (Israel) 

Revenue: $21.90 billion
Revenue from Pharmaceutical Drug Sales: $21.90 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $2.11 billion
Number of Employees: 43,000
Revenue Per Employee: $509,000

Teva Pharmaceutical Industries is an Israeli multinational pharmaceutical company and specializes primarily in generic drugs, but other business interests include active pharmaceutical ingredients and, to a lesser extent, proprietary pharmaceuticals. It is the largest generic drug manufacturer in the world. Teva manufactures Copaxone, now the world’s best selling Multiple Sclerosis drug.

Top Pharmaceutical Companies

12. Amgen Inc (US) 

Revenue: $22,91 billion
Revenue from Pharmaceutical Drug Sales: $22,91 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $3,84 billion
Number of Employees: 19,200
Revenue Per Employee: $1,193,000

Amgen Inc. is an American multinational biopharmaceutical company headquartered in California, United States and is one of the world’s largest independent biotechnology firm. In 2013, the company’s largest selling product lines were Neulasta/Neupogen, two closely related drugs used to prevent infections in patients undergoing cancer chemotherapy; and Enbrel, a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases. Other products include Epogen, Aranesp, Sensipar/Mimpara, Nplate, Vectibix, Prolia and XGEVA.

Top Pharmaceutical Companies

11. AstraZeneca plc (UK) 

Revenue: $23,00 billion
Revenue from Pharmaceutical Drug Sales: $23,00 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $5,89 billion
Number of Employees: 50,000
Revenue Per Employee: $460,000

AstraZeneca plc was founded 1999, through the merger of the Sweden-based Astra AB and the UK-based Zeneca Group, is a Swedish-British multinational pharmaceutical and biologics company. It specializes in prescriptive medicines including Carbocaine, Naropin, Betaloc, Zestril, lexinor, Cubicin, Zomig, Tomudex, and a variety of other medicines in the areas of oncology, neuroscience, gastrointestinal, etc. The acid reflux medication called Nexium is its leading product at $5.2 billion. It is also the manufacturer of drugs for cholesterol treatment called Crestor and antipsychotic drug called Seroquel.

Top Pharmaceutical Companies

10. Bayer AG (Germany) 

Revenue: $49.10 billion
Revenue from Pharmaceutical Drug Sales: $17,40 billion
Percent of Revenue From Pharmaceutical Drug Sales: 35%
Estimated R&D Spend: $4,89 billion
Number of Employees: 115,200
Revenue Per Employee: $426,000

Bayer, the creators of world-famous drug Aspirin, is a German pharmaceutical company that was established nearly 150 years ago in 1863. Bayer joins the 2017 list of top 10 pharmaceutical companies thanks to a surge of sales from drug Xarelto, used to treat blood clots and injection Eylea, for retina disease. Contributing to its success was the decision to take a $66 billion merger with Monsanto, a US-based agriculture biotechnology company. The merger is expected to give Bayer an extra boost that will continue to drive up sales and investment in the development of new drugs and treatments.

Top Pharmaceutical Companies

9. AbbVie Inc. (US) 

Revenue: $25.65 billion
Revenue from Pharmaceutical Drug Sales: $25.65 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $4.33 billion
Number of Employees: 30,000
Revenue Per Employee: $855,000

AbbVie is an American biopharmaceutical company formed in 2013 and was formed when Abbott Laboratories announced its plan to separate into two publicly traded companies. It was decided that”new” Abbott Laboratories would specialize in diversified products including medical devices, diagnostic equipment and nutrition products, while AbbVie would operate as a research-based pharmaceutical manufacturer that specialises in making small molecule drugs for patients worldwide.

The company focuses on therapy areas such as dermatology, oncology, neurological disorders and metabolic diseases.

AbbVie’s most well known for its rheumatoid arthritis med Humira (Humira makes up more than 60% of AbbVie’s total sales) along with Imbruvica, Lupron, Veikira and Synthroid.

Top Pharmaceutical Companies

8. Gilead Sciences (US) 

Revenue: $34.40 billion
Revenue from Pharmaceutical Drug Sales: $29.50 billion
Percent of Revenue From Pharmaceutical Drug Sales: 99%
Estimated R&D Spend: $3.40 billion
Number of Employees: 9,100
Revenue Per Employee: $3,370,000

Gilead is a research-based biopharma company and retains the same spot among pharma’s top 10 list as last year. In 2016, the company gained regulatory approval for Vemlidy, used to treat chronic hepatitis B virus infections. Historically, Gilead focused on developing antiviral drugs for infectious diseases like HIV and hepatitis B/C, however, the company has branched out into other areas such as pulmonary diseases. Although 2016 antiviral drug sales accounted for 90% of total revenue, the amount accumulated from other pharmaceutical sales has risen by 13.6% since 2015.

Top Pharmaceutical Companies

7. GlaxoSmithKline plc (UK)

Revenue: $34.5 billion
Revenue from Pharmaceutical Drug Sales: $19.70 billion
Percent of Revenue From Pharmaceutical Drug Sales: 57%
Estimated R&D Spend: $4.51 billion
Number of Employees: 93,100
Revenue Per Employee: $370,000

GlaxoSmithKline PLC is a multinational company based in the United Kingdom dealing in the fields of pharmaceutical, biologics, vaccines and consumer healthcare. GSK was formed by the merger of Glaxo Wellcome plc and SmithKline Beecham plc in 2000. It manufactures products for various diseases including mental health, diabetes, asthma, cancer, virus control, etc. GSK also manufactures nutritional products, drinks and other healthcare goods like Horlicks, sensodyne, Boost, etc. Its top selling drug is Advair and is used to treat asthema and chronic obstructive pulmonary disorder treatment.

Top Pharmaceutical Companies

6. Sanofi S.A. (France)

Revenue: $33.83 billion
Revenue from Pharmaceutical Drug Sales: $33.83 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $5.48 billion
Number of Employees: 110,100
Revenue Per Employee: $307,500

Sanofi-Aventis, a French multinational pharmaceutical company. Its headquarters are located in Paris, France. It conducts research and development and manufactures pharmaceutical products sold primarily in the prescription market. Over-the-counter medicines are also developed by the company. Various drugs manufactured by the company include Aflibercept, Jevtana, Humenza vaccine, Iniparib and Otamixaban. Sanofi-Aventis was formed in 2004 by the merger of Aventis and Sanofi-Synthélabo and later in 2011 changed the name to Sanofi.

Top Pharmaceutical Companies

5. Merck & Co., Inc (US)

Revenue: $39.80 billion
Revenue from Pharmaceutical Drug Sales: $35.15 billion
Percent of Revenue From Pharmaceutical Drug Sales: 88%
Estimated R&D Spend: $10.12 billion
Number of Employees: 70,000
Revenue Per Employee: $585,000

Merck & Co., Inc. is an American pharmaceutical company with its headquarters located in Whitehouse Station, New Jersey. Kenneth Frazier is the chairman, president and CEO of the company and it was founded in 1891 as a subsidiary of Merck KGaA. It came out as an independent company in 1917 after being taken over by US Government during World War I.

Top Pharmaceutical Companies

4. Novartis International AG (Switzerland)

Revenue: $48.50 billion
Revenue from Pharmaceutical Drug Sales: $32.50 billion
Percent of Revenue From Pharmaceutical Drug Sales: 67%
Estimated R&D Spend: $9.10 billion
Number of Employees: 118,700
Revenue Per Employee: $408,000

Novartis International AG, a multinational pharmaceutical company is based in Basel, Switzerland. Novartis has been on the face of the pharmaceutical industry for about 250 years owing to its formation by merger of Swiss companies Ciba-Geigy and Sandoz Laboratories in 1996. Novartis produces a range of products including vaccines, contact lenses, over-the- counter drugs, veterinary medicines, etc. Novartis is a manufacturer of drugs including clozapine, diclofenac, carbamazepine, valsartan (Diovan) and Glivec.

Top Pharmaceutical Companies

3. Hoffmann-La Roche AG (Switzerland)

Revenue: $50.00 billion
Revenue from Pharmaceutical Drug Sales: $39,50 billion
Percent of Revenue From Pharmaceutical Drug Sales: 76%
Estimated R&D Spend: – $10,01 billion
Number of Employees: 94,000
Revenue Per Employee: $531,000

Hoffmann-La Roche is a Swiss global healthcare company founded by Fritz Hoffmann-La Roche after whom the company is named, in 1896. Its headquarters is located in Basel, Switzerland. Other companies owned by Roche are Genentech, Chugai pharmaceuticals and Ventana. It was the first company to produce synthetic vitamin C at a large scale under the brand name of Redoxon. Its leading drug is Herceptin a medication for breast cancer. The various drugs produced by Roche include Accutane, Bactrium, Cellcept, Herceptin, Invirase, Tamiflu, Rohypnol, etc. It also manufactures a range of Diabetes management products under the brand name Accu-check.

Top Pharmaceutical Companies

2. Pfizer Inc (US)

Revenue: $52.83 billion
Revenue from Pharmaceutical Drug Sales: $52.83 billion
Percent of Revenue From Pharmaceutical Drug Sales: 100%
Estimated R&D Spend: $7.90 billion
Number of Employees: 96,500
Revenue Per Employee: $548,000

Pfizer is the world’s largest research-based pharmaceutical company. Its research headquarters are located in Groton, Connecticut, America. Pfizer has developed many medicines and vaccines like Sutent, Zithromax, apixaban, Macugen, Lyrica, latreperdine, etc. in the areas of oncology, infections and infestations, cardiology, opthamalogy, neurology and psychiatry. Its top selling drug is Lipitor. The company was founded in 1849 in New York City by cousins Charles Pfizer and Charles Erhart.

Top Pharmaceutical Companies

1. Johnson & Johnson (US)

Revenue: $71.89 billion
Revenue from Pharmaceutical Drug Sales: $33.50 billion
Percent of Revenue From Pharmaceutical Drug Sales: 47%
Estimated R&D Spend: $9.10 billion
Number of Employees: 127,100
Revenue Per Employee: $565,000

Johnson & Johnson is a US based multinational company which manufactures medical devices, pharmaceuticals and consumer packaged goods. It was founded in 1886 by Robert wood Johnson I, James Wood Johnson and Edward Mead Johnson. The Company’s headquarters is located in New Brunswick, New Jersey. Johnson & Johnson is a leading name in many household items like Johnson & Johnson baby products, Neutrogena skin and beauty products, Band-Aid, Clean and clear facewashes, etc. The other drugs manufactured by it are Bapineuzumab, ceftobiprole, dacogen, procrit, rivaroxaban, topamax, etc.